Name : MEK2(Ser226) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN5247018889
| Long name | MEK2(Ser226) Primary Polyclonal Antibody |
| Also known as | MEK2(Ser226) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | MEK2 Ser226 |
| Specificity | This is a highly specific antibody against MEK2 Ser226 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Ser226 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human MEK2 around the phosphorylation site of Ser226 |
| Gene ID number | 5605 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | A pseudogene, It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3, Jul 2008], Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases, The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax, This kinase is known to play a critical role in mitogen growth factor signal transduction, [provided by RefSeq, a disease characterized by heart defects, and distinctive facial features similar to those found in Noonan syndrome, has been identified for this gene, mental retardation, which is located on chromosome 7, The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CFC syndrome, Cardiofaciocutaneous syndrome, Dual specicity mitogen activated protein kinase kinase 2, Dual specicity mitogen-activated protein kinase kinase 2, ERK activator kinase 2, FLJ26075, MAP kinase kinase 2, MAP2K 2, MAPK / ERK kinase 2, MAPK/ERK kinase 2, MAPKK 2, MAPKK2, MEK 2, MEK2, MKK 2, MKK2, MP2K2_HUMAN, Microtubule Associated Protein Kinase Kinase 2, Mitogen activated protein kinase kinase 2, Mitogen activated protein kinase kinase 2 p45, OTTHUMP00000165826, OTTHUMP00000165827, PRKMK 2, PRKMK2 V, map2k2, MAP2K2phospho S226 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | MEK2(Ser226) |
| Short name | MEK2(Ser226) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | MEK2(Ser226) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6842 |
| Gene | MAP2K2 |
| Long gene name | mitogen-activated protein kinase kinase 2 |
| Synonyms gene | PRKMK2 |
| Synonyms | MEK2 |
| Locus | 19p13, 3 |
| Discovery year | 1993-11-05 |
| GenBank acession | L11285 |
| Entrez gene record | 5605 |
| Pubmed identfication | 8388392 |
| Classification | Mitogen-activated protein kinase kinases |
| Havana BLAST/BLAT | OTTHUMG00000134286 |
| Locus Specific Databases | LRG_750 |