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MEK2(Ser226) Antibody, Biotin Conjugated

MEK2(Ser226) Antibody, Biotin Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Biotin Conjugated, MEK2(Ser226) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMEK2 Ser226
SpecificityThis is a highly specific antibody against MEK2 Ser226
ModificationPhosphorylation
Modification siteSer226
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human MEK2 around the phosphorylation site of Ser226
Gene ID number5605
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A pseudogene, It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3, Jul 2008], Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases, The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax, This kinase is known to play a critical role in mitogen growth factor signal transduction, [provided by RefSeq, a disease characterized by heart defects, and distinctive facial features similar to those found in Noonan syndrome, has been identified for this gene, mental retardation, which is located on chromosome 7, The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms MEK2
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetMEK2(Ser226) Conjugated
Short name Conjugated, MEK2(Ser226) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, MEK2(Ser226) (Antibody to)
Alternative techniqueantibodies
Identity 6842
Gene MAP2K2
Long gene name mitogen-activated protein kinase kinase 2
Synonyms gene PRKMK2
Locus 19p13, 3
Discovery year 1993-11-05
GenBank acession L11285
Entrez gene record 5605
Pubmed identfication 8388392
Classification Mitogen-activated protein kinase kinases
Havana BLAST/BLAT OTTHUMG00000134286
Locus Specific Databases LRG_750

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