Name : MEK2(Ser226) Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN8311916687
| Long name | FITC Conjugated, MEK2(Ser226) Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | MEK2 Ser226 |
| Specificity | This is a highly specific antibody against MEK2 Ser226 |
| Modification | Phosphorylation |
| Modification site | Ser226 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human MEK2 around the phosphorylation site of Ser226 |
| Gene ID number | 5605 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | A pseudogene, It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3, Jul 2008], Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases, The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax, This kinase is known to play a critical role in mitogen growth factor signal transduction, [provided by RefSeq, a disease characterized by heart defects, and distinctive facial features similar to those found in Noonan syndrome, has been identified for this gene, mental retardation, which is located on chromosome 7, The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | MEK2 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | MEK2(Ser226) Conjugated |
| Short name | FITC Conjugated, MEK2(Ser226) Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, MEK2(Ser226) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6842 |
| Gene | MAP2K2 |
| Long gene name | mitogen-activated protein kinase kinase 2 |
| Synonyms gene | PRKMK2 |
| Locus | 19p13, 3 |
| Discovery year | 1993-11-05 |
| GenBank acession | L11285 |
| Entrez gene record | 5605 |
| Pubmed identfication | 8388392 |
| Classification | Mitogen-activated protein kinase kinases |
| Havana BLAST/BLAT | OTTHUMG00000134286 |
| Locus Specific Databases | LRG_750 |