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MEK2(Ser226) Antibody, FITC Conjugated

MEK2(Ser226) Antibody, FITC Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name FITC Conjugated, MEK2(Ser226) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMEK2 Ser226
SpecificityThis is a highly specific antibody against MEK2 Ser226
ModificationPhosphorylation
Modification siteSer226
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human MEK2 around the phosphorylation site of Ser226
Gene ID number5605
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A pseudogene, It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3, Jul 2008], Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases, The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax, This kinase is known to play a critical role in mitogen growth factor signal transduction, [provided by RefSeq, a disease characterized by heart defects, and distinctive facial features similar to those found in Noonan syndrome, has been identified for this gene, mental retardation, which is located on chromosome 7, The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms MEK2
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetMEK2(Ser226) Conjugated
Short name FITC Conjugated, MEK2(Ser226) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, MEK2(Ser226) (Antibody to)
Alternative techniqueantibodies
Identity 6842
Gene MAP2K2
Long gene name mitogen-activated protein kinase kinase 2
Synonyms gene PRKMK2
Locus 19p13, 3
Discovery year 1993-11-05
GenBank acession L11285
Entrez gene record 5605
Pubmed identfication 8388392
Classification Mitogen-activated protein kinase kinases
Havana BLAST/BLAT OTTHUMG00000134286
Locus Specific Databases LRG_750

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