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MEK5 Antibody

MEK5 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMEK5 Primary Polyclonal Antibody
Also known asMEK5 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMEK5
SpecificityThis is a highly specific antibody against MEK5
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range380-430/448
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MEK5
Gene ID number4217
Swiss ProtQ99683
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Both p38 MAPK and JNKs control the transcription factors activator protein-1 (AP-1), MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7, MAP3K5/ASK1 is required for the innate immune response, Mediates signal transduction of various stressors like oxidative stress as well as by receptor-mediated inflammatory signals, Mediates signaling for determination of cell fate such as differentiation and survival, Once activated, Plays a crucial role in the apoptosis signal transduction pathway through mitochondria-dependent caspase activation, Plays an important role in the cascades of cellular responses evoked by changes in the environment, These MAP2Ks in turn activate p38 MAPKs and c-jun N-terminal kinases (JNKs), acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K4/SEK1, such as the tumor necrosis factor (TNF) or lipopolysaccharide (LPS), which is essential for host defense against a wide range of pathogens, Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ASK-1, Apoptosis signal-regulating kinase 1, MAP3K5, MAPK/ERK kinase kinase 5, MAPKKK5, MEK kinase 5, MEKK 5, MEKK5, Mitogen-activated protein kinase kinase kinase 5, ASK1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMEK5
Short nameMEK5 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMEK5 (Antibody to)
Alternative techniqueantibodies
Identity 6845
Gene MAP2K5
Long gene name mitogen-activated protein kinase kinase 5
Synonyms gene PRKMK5
Synonyms MEK5 MAPKK5 HsT17454
Locus 15q23
Discovery year 1997-11-11
GenBank acession U25265
Entrez gene record 5607
Pubmed identfication 7759517
RefSeq identity NM_145162
Classification Mitogen-activated protein kinase kinases
Havana BLAST/BLAT OTTHUMG00000133264

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