Filters

MEK5(Ser142) Antibody

MEK5(Ser142) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMEK5(Ser142) Primary Polyclonal Antibody
Also known asMEK5(Ser142) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMEK5 Ser142
SpecificityThis is a highly specific antibody against MEK5 Ser142
Modification(s)Phosphorylation
Modification site(s)Ser142
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human MEK5 around the phosphorylation site of Ser142
Gene ID number5607
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen (MAP kinase kinase family), It is activated by phosphorylation on Ser/Thr by MAP kinase kinases and interacts specifically with ERK5, It is not phosphorylated by RAFA, MEK5 is expressed in many adult tissues and is most abundant in heart and skeletal muscle, RAFB or RAFC and it may interact with GTPases such as CDC42, The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation, This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, This kinase specifically interacts with and activates MAPK7/ERK5, and not with another MAP kinase like P38, as well as by atypical protein kinase C isoforms (aPKCs), MEK5 is a dual specificity protein kinase belonging to thr Ser/Thr protein kinase family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Dual specicity mitogen activated protein kinase kinase 5, Dual specicity mitogen-activated protein kinase kinase 5, EC 2, MAP kinase kinase 5, MAP kinase kinase MEK5b, MAP2K5, MAPK/ERK kinase 5, MAPK/ERK kinase 5, MAPKK 5, MAPKK5, MEK 5, MP2K5_HUMAN, PRKMK5, 2, 7, 12, MAP2K5 phospho S142
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMEK5(Ser142)
Short nameMEK5(Ser142) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMEK5(Ser142) (Antibody to)
Alternative techniqueantibodies
Identity 6845
Gene MAP2K5
Long gene name mitogen-activated protein kinase kinase 5
Synonyms gene PRKMK5
Synonyms MEK5 MAPKK5 HsT17454
Locus 15q23
Discovery year 1997-11-11
GenBank acession U25265
Entrez gene record 5607
Pubmed identfication 7759517
RefSeq identity NM_145162
Classification Mitogen-activated protein kinase kinases
Havana BLAST/BLAT OTTHUMG00000133264

Similar products

Subscribe to our Newsletter