Name : MEK5(Ser142) Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN3122663199
| Long name | ALEXA FLUOR 555 Conjugated, MEK5(Ser142) Polyclonal Antibody |
| Also known as | Anti-MEK5 Ser142 PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | MEK5 Ser142 |
| Specificity | This is a highly specific antibody against MEK5 Ser142 |
| Modification | Phosphorylation |
| Modification Site | Ser142 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human MEK5 around the phosphorylation site of Ser142 |
| Gene ID Number | 5607 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | (MAP kinase kinase family), It is activated by phosphorylation on Ser/Thr by MAP kinase kinases and interacts specifically with ERK5, It is not phosphorylated by RAFA, MEK5 is expressed in many adult tissues and is most abundant in heart and skeletal muscle, RAFB or RAFC and it may interact with GTPases such as CDC42, The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation, This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, This kinase specifically interacts with and activates MAPK7/ERK5, and not with another MAP kinase like P38, as well as by atypical protein kinase C isoforms (aPKCs), MEK5 is a dual specificity protein kinase belonging to thr Ser/Thr protein kinase family |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | MEK5 MAPKK5 HsT17454 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | MEK5(Ser142) |
| Short name | MEK5(Ser142) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, MEK5(Ser142) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6845 |
| Gene | MAP2K5 |
| Long gene name | mitogen-activated protein kinase kinase 5 |
| Synonyms gene | PRKMK5 |
| Locus | 15q23 |
| Discovery year | 1997-11-11 |
| GenBank acession | U25265 |
| Entrez gene record | 5607 |
| Pubmed identfication | 7759517 |
| RefSeq identity | NM_145162 |
| Classification | Mitogen-activated protein kinase kinases |
| Havana BLAST/BLAT | OTTHUMG00000133264 |