Filters

MEK6 Antibody (MKK6)

MEK6 Antibody (MKK6) size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenMEK6 (MKK6)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
Notes Titration of the MEK6 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis MEK6 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P52564
PurityAntigen affinity
Description Han et al, MKK6 is a member of the dual specificity protein kinase family, Mukherjee et al, They proposed that ser and/or thr acetylation by a bacterial effector may be a mechanism that occurs in other signaling pathways, also known as MAP kinase kinase 6 (MAPKK6 or MKK6) and MAPK/ERK kinase 6 (MEK6) is an enzyme that in humans is encoded by the MAP2K6 gene, on chromosome 17, thereby blocking phosphorylation and kinase activation, using coenzyme A to modify critical ser and thr residues in the MKK6 activation loop, which functions as a mitogen-activated protein (MAP) kinase kinase, (1996) described experiments addressing the function of MKK6 in intracellular signaling pathways leading toward activation of p38 MAPK, (2006) found that the Yersinia YopJ virulence factor acted as an acetyltransferase, MAP2K6 (Mitogen-activated protein kinase kinase 6)
ImmunogenAn amino acid sequence from the N-terminus of human MKK6/MEK6 (KKRNPGLKIPKEAFEQP) was used as the immunogen for this MEK6 antibody (100% mouse homology)
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MEK6 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetMEK6 (MKK6)
Short nameMEK6 Antibody (MKK6)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMEK6 (Antibody to) (MKK6)
Alternative techniqueantibodies
Identity 6846
Gene MAP2K6
Long gene name mitogen-activated protein kinase kinase 6
Synonyms gene PRKMK6
Synonyms MEK6 MKK6 SAPKK3 MAPKK6
Synonyms name kinase 6 (MAP kinase kinase 6) , mitogen-activated, protein kinase
Locus 17q24, 3
Discovery year 1997-11-11
GenBank acession U39064
Entrez gene record 5608
Pubmed identfication 8621675
RefSeq identity NM_002758
Classification Mitogen-activated protein kinase kinases
Havana BLAST/BLAT OTTHUMG00000180311

Similar products

Subscribe to our Newsletter