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MEL18 Antibody, ALEXA FLUOR 350

MEL18 Antibody, ALEXA FLUOR 350 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 350 Conjugated, MEL18 Polyclonal Antibody
Also known asAnti-MEL18 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMEL18
SpecificityThis is a highly specific antibody against MEL18
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range170-210/344
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MEL18
Gene ID Number7703
Swiss ProtP35227
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Also plays a role in antero-posterior specification of the axial skeleton and negative regulation of the self-renewal activity of hematopoietic stem cells, Binds specifically to the DNA sequence 5'-GACTNGACT-3', Component of a Polycomb group (PcG) multiprotein PRC1-like complex, Has tumor suppressor activity, Is not functionally redundant with BMI1, May play a role in control of cell proliferation and/or neural cell development, PcG PRC1 complex acts via chromatin remodeling and modification of histones, Regulates proliferation of early T progenitor cells by maintaining expression of HES1, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility, throughout development, unlike BMI1 does not stimulate the E3 ubiquitin-protein ligase activity in a reconstituted PRC1-like complex (By similarity), Transcriptional repressor
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms DNA-binding protein Mel-18, MEL18, PCGF2, Polycomb group RING finger protein 2, RING finger protein 110, RNF110, ZNF144, Zinc finger protein 144, MEL-18
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetMEL18
Short nameMEL18 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, MEL18 (Antibody to)
Alternative techniqueantibodies

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