Name : Menin Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN3361648811
| Long name | Menin Primary Polyclonal Antibody |
| Also known as | Menin PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Menin |
| Specificity | This is a highly specific antibody against Menin |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 560-612/615 |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Menin |
| Gene ID number | 4221 |
| Swiss Prot | O00255 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Binds to the TERT promoter and represses telomerase expression, Functions as a transcriptional regulator, May be involved in DNA repair, May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity), Plays a role in TGFB1-mediated inhibition of cell-proliferation, Positively regulates HOXC8 and HOXC6 gene expression, Represses JUND-mediated transcriptional activation on AP1 sites, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4), as well as that mediated by NFKB subunit RELA, possibly regulating SMAD3 transcriptional activity, Essential component of a MLL/SET1 histone methyltransferase (HMT) complex |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | MEN1, Menin, SCG2, MEAI |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Menin |
| Short name | Menin Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Menin (Antibody to) |
| Alternative technique | antibodies |
| Identity | 7010 |
| Gene | MEN1 |
| Long gene name | menin 1 |
| Synonyms gene name | multiple endocrine neoplasia I |
| Synonyms name | menin |
| Locus | 11q13 |
| Discovery year | 2001-06-22 |
| GenBank acession | U93236 |
| Havana BLAST/BLAT | OTTHUMG00000045366 |
| Locus Specific Databases | UMD Locus Specific Databases LRG_509 |