Name : Menin Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN8412885859
| Long name | ALEXA FLUOR 488 Conjugated, Menin Polyclonal Antibody |
| Also known as | Anti-Menin PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Menin |
| Specificity | This is a highly specific antibody against Menin |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 560-612/615 |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Menin |
| Gene ID Number | 4221 |
| Swiss Prot | O00255 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Binds to the TERT promoter and represses telomerase expression, Functions as a transcriptional regulator, May be involved in DNA repair, May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity), Plays a role in TGFB1-mediated inhibition of cell-proliferation, Positively regulates HOXC8 and HOXC6 gene expression, Represses JUND-mediated transcriptional activation on AP1 sites, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4), as well as that mediated by NFKB subunit RELA, possibly regulating SMAD3 transcriptional activity, Essential component of a MLL/SET1 histone methyltransferase (HMT) complex |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Menin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | Menin |
| Short name | Menin Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, Menin (Antibody to) |
| Alternative technique | antibodies |
| Identity | 7010 |
| Gene | MEN1 |
| Long gene name | menin 1 |
| Synonyms gene name | multiple endocrine neoplasia I |
| Synonyms name | menin |
| Locus | 11q13 |
| Discovery year | 2001-06-22 |
| GenBank acession | U93236 |
| Havana BLAST/BLAT | OTTHUMG00000045366 |
| Locus Specific Databases | UMD Locus Specific Databases LRG_509 |