Name : Merlin (Ser518) Antibody, HRP Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :368
SKU : GEN3890647213
| Long name | HRP Conjugated, Merlin (Ser518) Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | HRP Conjugated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Merlin (Ser518) |
| Specificity | This is a highly specific antibody against Merlin (Ser518) |
| Modification | Phosphorylation |
| Modification site | Ser518 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 500-545/590 |
| Subcellular location | Cell membrane, Nucleus, Cytoplasm |
| Source | KLH conjugated synthetic phosphopeptide derived from human Merlin around the phosphorylation site of Ser518 |
| Gene ID number | 4771 |
| Swiss Prot | P35240 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, May act as a membrane stabilizing protein, May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity, Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis, Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | BANF, Merlin, Moesin-ezrin-radixin-like protein, NF2, Neurofibromin-2, SCH, Schwannomerlin, Schwannomin, ACN |
| Properties | Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase  |
| Gene target | Merlin (Ser518) Conjugated |
| Short name | Conjugated, Merlin (Ser518) Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | HRP |
| Alternative name | horseradish peroxidase coupled, Merlin (Ser518) (Antibody to) |
| Alternative technique | antibodies |