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Met (c Met) Antibody, ALEXA FLUOR 488

Met (c Met) Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, Met (c Met) Polyclonal Antibody
Also known asAnti-Met (c-Met) PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMet (c-Met)
SpecificityThis is a highly specific antibody against Met (c-Met)
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range25-75/1390
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Met (c-Met)
Gene ID Number4233
Swiss ProtP08581
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Acts as a receptor for Listeria internalin inlB, During embryonic development, Following activation by ligand, GRB2, In adults, Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules, MET signaling plays a role in gastrulation, PI3 kinase-AKT, PLCG1, Promotes also differentiation and proliferation of hematopoietic cells, Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, Regulates many physiological processes including proliferation, SRC, STAT3 or the adapter GAB1, The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects, angiogenesis and kidney formation, development and migration of muscles and neuronal precursors, interacts with the PI3-kinase subunit PIK3R1, mediating entry of the pathogen into cells, morphogenesis and survival, or PLCgamma-PKC, participates in wound healing as well as organ regeneration and tissue remodeling, scattering, Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms AUTS9, HGF receptor, HGF/SF receptor, Hepatocyte growth factor receptor, MET, Proto-oncogene c-Met, RCCP2, SF receptor, Scatter factor receptor, Tyrosine-protein kinase Met, c-Met, HGFR
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Met (c Met) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetMet (c Met)
Short nameMet (c Met) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, Met (c Met) (Antibody to)
Alternative techniqueantibodies

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