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Met (c Met) Antibody, PE Conjugated

Met (c Met) Antibody, PE Conjugated size: 0.1ml 368

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 368
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name PE Conjugated, Met (c Met) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationPE
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMet (c-Met)
SpecificityThis is a highly specific antibody against Met (c-Met)
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range25-75/1390
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human Met (c-Met)
Gene ID number4233
Swiss ProtP08581
Tested applicationsFCM
Recommended dilutionsFCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Acts as a receptor for Listeria internalin inlB, During embryonic development, Following activation by ligand, GRB2, In adults, Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules, MET signaling plays a role in gastrulation, PI3 kinase-AKT, PLCG1, Promotes also differentiation and proliferation of hematopoietic cells, Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, Regulates many physiological processes including proliferation, SRC, STAT3 or the adapter GAB1, The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects, angiogenesis and kidney formation, development and migration of muscles and neuronal precursors, interacts with the PI3-kinase subunit PIK3R1, mediating entry of the pathogen into cells, morphogenesis and survival, or PLCgamma-PKC, participates in wound healing as well as organ regeneration and tissue remodeling, scattering, Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission480, 565nm/578nm
Synonyms AUTS9, HGF receptor, HGF/SF receptor, Hepatocyte growth factor receptor, MET, Proto-oncogene c-Met, RCCP2, SF receptor, Scatter factor receptor, Tyrosine-protein kinase Met, c-Met, HGFR
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetMet (c Met) PE Conjugated
Short name PE Conjugated, Met (c Met) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelPE
Alternative name peroxidase coupled, Met (c Met) (Antibody to)
Alternative techniqueantibodies

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