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MGLUR1 + MGLUR5 Antibody

MGLUR1 + MGLUR5 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMGLUR1 + MGLUR5 Primary Polyclonal Antibody
Also known asMGLUR1 + MGLUR5 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMGLUR1 + MGLUR5
SpecificityThis is a highly specific antibody against MGLUR1 + MGLUR5
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MGLUR1 + MGLUR5
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen AMPA and kainite receptors that are involved in the fast excitatory synaptic transmission, For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, Group-I receptors stimulate phospholipase C as revealed by an increase in phosphoinositide turnover and calcium release from internal stores, Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase, In expression systems, Recently, The Group-I receptors include Metabotropic Glutamate Receptor 5 and Metabotropic Glutamate Receptor 1a, The Group-II receptors in include mGluR2 and mGluR3, These receptors are called metabotropic glutamate receptors, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins, Glutamate is the main excitatory neurotransmitter in the brain
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GPRC1A, GPRC1E, GRM1, GRM1A, GRM1_HUMAN, GRM5, GRM5_HUMAN, MGLUR1, MGLUR1A, MGLUR5, MGLUR5B, Metabotropic glutamate receptor 1, Metabotropic glutamate receptor 5, mGlu1, mGlu5, MGLUR1+MGLUR5
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMGLUR1 + MGLUR5
Short nameMGLUR1 + MGLUR5 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMGLUR1 and MGLUR5 (Antibody to)
Alternative techniqueantibodies
Identity 4597
Gene GRM5
Long gene name glutamate metabotropic receptor 5
Synonyms gene name glutamate receptor, metabotropic 5
Synonyms MGLUR5 GPRC1E mGlu5 PPP1R86
Synonyms name protein phosphatase 1, regulatory subunit 86
Locus 11q14, 2-q14, 3
Discovery year 1993-10-22
GenBank acession D28538
Entrez gene record 2915
Pubmed identfication 7908515
RefSeq identity NM_000842
Classification Glutamate metabotropic receptors Protein phosphatase 1 regulatory subunits
Havana BLAST/BLAT OTTHUMG00000134306

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