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MGMT (888CT22.2.4) Monoclonal Antibody

MGMT (888CT22.2.4) Monoclonal Antibody size: 0.1ml 211

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 211
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name2, 4) Monoclonal Antibody, MGMT (888CT22
Also known as2, 4) Monoclonal Antibody, MGMT (888CT22
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMGMT
SpecificityThis is a highly specific antibody against MGMT
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number2, 4, 888CT22
SourcePurified His-tagged MGMT protein was used to produced this monoclonal antibody
Gene ID number4255
Swiss ProtP16455
Tested Applications IF, IHC-P, WB
Recommended dilutions IF(1:25), IHC-P(1:25), WB(1:1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme, This is a suicide reaction: the enzyme is irreversibly inactivated, Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA
Purification method This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase, Methylated-DNA--protein-cysteine methyltransferase
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target2, 4) Monoclonal, MGMT (888CT22
Short name2, 4) Monoclonal Antibody, MGMT (888CT22
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name2, 4) monoclonal (Antibody to), O-6-methylguanine-Desoxyribonucleic acid methyltransferase (888CT22
Alternative techniqueantibodies
Alternative to gene target DNA-methyltransferase activity, MGMT and IDBG-93188 and ENSG00000170430 and 4255, Mgmt and IDBG-211408 and ENSMUSG00000054612 and 17314, nuclei, this GO :0003677 and DNA binding and molecular function this GO :0003824 and catalytic activity and molecular function this GO :0003908 and methylated-DNA-[protein]-cysteine S-methyltransferase activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0006266 and DNA ligation and biological process this GO :0006281 and DNA repair and biological process this GO :0006306 and DNA methylation and biological process this GO :0006307 and DNA dealkylation involved in DNA repair and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0008168 and methyltransferase activity and molecular function this GO :0009008 and DNA-methyltransferase activity and molecular function this GO :0009636 and response to toxic substance and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016020 and membrane and cellular component this GO :0034599 and cellular response to oxidative stress and biological process this GO :0042493 and response to drug and biological process this GO :0043281 and regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0045471 and response to ethanol and biological process this GO :0045739 and positive regulation of DNA repair and biological process this GO :0051593 and response to folic acid and biological process this GO :0060548 and negative regulation of cell death and biological process this GO :0060644 and mammary gland epithelial cell differentiation and biological process this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071479 and cellular response to ionizing radiation and biological process, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003824: catalytic activity and also this GO :0003908: methylated-DNA-[protein]-cysteine S-methyltransferase activity and also this GO :0005509: calcium ion binding and also this GO :0008168: methyltransferase activity and also this GO :0009008: DNA-methyltransferase activity, this GO :0003824: catalytic activity, this GO :0003908: methylated-DNA-[protein]-cysteine S-methyltransferase activity, this GO :0005509: calcium ion binding, this GO :0008168: methyltransferase activity, this GO :0009008: DNA-methyltransferase activity, O-6-methylguanine-DNA methyltransferase
Identity 7059
Gene MGMT
Long gene name O-6-methylguanine-DNA methyltransferase
Synonyms name methylated-DNA--protein-cysteine methyltransferase
Locus 10q26, 3
Discovery year 1989-10-16
GenBank acession M29971
Entrez gene record 4255
RefSeq identity NM_002412
Havana BLAST/BLAT OTTHUMG00000019261

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