| Long name | MHC class I Primary Polyclonal Antibody |
| Also known as | MHC class I PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | MHC class I |
| Specificity | This is a highly specific antibody against MHC class I |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 60-105/181 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MHC class I |
| Swiss Prot | G0ZMJ8 |
| Tested Applications | FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions | FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen, Exon 1 encodes the leader peptide, Hundreds of HLA-A alleles have been described, Jul 2008], Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule, The heavy chain is anchored in the membrane, The heavy chain is approximately 45 kDa and its gene contains 8 exons, They are expressed in nearly all cells, This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin), Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation, [provided by RefSeq, and exons 6 and 7 encode the cytoplasmic tail, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, HLA-A belongs to the HLA class I heavy chain paralogues |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 1C04_HUMAN, A 9, Aw 24, Aw 68, CLASS I HISTOCOMPATIBILITY ANTIGEN, H2 K1, H2K, HLA A, HLA C, HLA class I histocompatibility antigen A 1 alpha chain, HLA class I histocompatibility antigen A 11 alpha chain, HLA class I histocompatibility antigen A 2 alpha chain, HLA class I histocompatibility antigen A 24 alpha chain, HLA class I histocompatibility antigen A 3 alpha chain, HLA class I histocompatibility antigen A 30 alpha chain, HLA class I histocompatibility antigen A 32 alpha chain, HLA class I histocompatibility antigen A 68 alpha chain, HLA-A, HLA-C, HLAA, MHC class I heavy chain H2 K, Major histocompatibility complex class I A, A 28 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | MHC class I |
| Short name | MHC class I Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Major histocompabitility complex class I (Antibody to) |
| Alternative technique | antibodies |
| Identity | 7092 |
| Gene | MICC |
| Long gene name | MHC class I polypeptide-related sequence C (pseudogene) |
| Synonyms gene name | MHC class I polypeptide-related sequence C |
| Synonyms | PERB11, 3 |
| Locus | 6p22, 1 |
| Discovery year | 1994-09-07 |
| Entrez gene record | 100129192 |
| Pubmed identfication | 8022771 |
| RefSeq identity | NG_027534 |
| Havana BLAST/BLAT | OTTHUMG00000031078 |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue