Name : MHC class I Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN7888357721
| Long name | ALEXA FLUOR 555 Conjugated, MHC class I Polyclonal Antibody |
| Also known as | Anti-MHC class I PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | MHC class I |
| Specificity | This is a highly specific antibody against MHC class I |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 60-105/181 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MHC class I |
| Swiss Prot | G0ZMJ8 |
| Tested applications | IF(IHC-P), FCM |
| Recommended dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity | Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen, Exon 1 encodes the leader peptide, Hundreds of HLA-A alleles have been described, Jul 2008], Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule, The heavy chain is anchored in the membrane, The heavy chain is approximately 45 kDa and its gene contains 8 exons, They are expressed in nearly all cells, This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin), Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation, [provided by RefSeq, and exons 6 and 7 encode the cytoplasmic tail, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, HLA-A belongs to the HLA class I heavy chain paralogues |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | PERB11, 3 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | MHC class I |
| Short name | MHC class I Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, Major histocompabitility complex class I (Antibody to) |
| Alternative technique | antibodies |
| Identity | 7092 |
| Gene | MICC |
| Long gene name | MHC class I polypeptide-related sequence C (pseudogene) |
| Synonyms gene name | MHC class I polypeptide-related sequence C |
| Locus | 6p22, 1 |
| Discovery year | 1994-09-07 |
| Entrez gene record | 100129192 |
| Pubmed identfication | 8022771 |
| RefSeq identity | NG_027534 |
| Havana BLAST/BLAT | OTTHUMG00000031078 |