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Mib1/Mindbomb Antibody, ALEXA FLUOR 488

Mib1/Mindbomb Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, Mib1/Mindbomb Polyclonal Antibody
Also known asAnti-Mib1/Mindbomb PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMib1/Mindbomb
SpecificityThis is a highly specific antibody against Mib1/Mindbomb
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Mib1/Mindbomb
Gene ID Number57534
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Although it seems to be widely expressed at low levels, Both DAPK and MIB1 are overexpressed in epileptic brain tissue, Delta, MIB1 also interacts with DAPK, MIB1 is expressed at highest concentrations in the CNS and ovary, MIB1 ubiquinates Delta by binding to its intracellular domain, Ubiquination of DAPK leads to inhibition of caspase-dependent apoptosis, a protein that plays an important role in the regulation of apoptosis, leading to the endocytosis and eventual degradation of the Delta receptor, paradoxically, results in the up-regulation of receptor activity and enhances Notch signaling, suggesting that they probably cooperate as regulators of neuronal death in epilepsy, therefore it is likely that overexpression of MIB1 can lead to tumor growth, which, MIB1 is a 1006 amino acid E3 ubiquitin ligase that activates the Notch ligand
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms DIP-1, Dip 1, Dip1, E3 ubiquitin protein ligase MIB 1, E3 ubiquitin protein ligase MIB1, E3 ubiquitin-protein ligase mib1, MIB1_HUMAN, Mind bomb homolog 1, Zinc finger ZZ type with ankyrin repeat domain protein 2, mib1, DAPK-interacting protein 1
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Mib1/Mindbomb Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetMib1/Mindbomb
Short nameMib1/Mindbomb Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, mindbomb E3 ubiquitin protein ligase 1/Mindbomb (Antibody to)
Alternative techniqueantibodies

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