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Mib1/Mindbomb Antibody, Cy7 Conjugated

Mib1/Mindbomb Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, Mib1/Mindbomb Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMib1/Mindbomb
SpecificityThis is a highly specific antibody against Mib1/Mindbomb
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human Mib1/Mindbomb
Gene ID number57534
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Although it seems to be widely expressed at low levels, Both DAPK and MIB1 are overexpressed in epileptic brain tissue, Delta, MIB1 also interacts with DAPK, MIB1 is expressed at highest concentrations in the CNS and ovary, MIB1 ubiquinates Delta by binding to its intracellular domain, Ubiquination of DAPK leads to inhibition of caspase-dependent apoptosis, a protein that plays an important role in the regulation of apoptosis, leading to the endocytosis and eventual degradation of the Delta receptor, paradoxically, results in the up-regulation of receptor activity and enhances Notch signaling, suggesting that they probably cooperate as regulators of neuronal death in epilepsy, therefore it is likely that overexpression of MIB1 can lead to tumor growth, which, MIB1 is a 1006 amino acid E3 ubiquitin ligase that activates the Notch ligand
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms DIP-1, Dip 1, Dip1, E3 ubiquitin protein ligase MIB 1, E3 ubiquitin protein ligase MIB1, E3 ubiquitin-protein ligase mib1, MIB1_HUMAN, Mind bomb homolog 1, Zinc finger ZZ type with ankyrin repeat domain protein 2, mib1, DAPK-interacting protein 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetMib1/Mindbomb Conjugated
Short name Conjugated, Mib1/Mindbomb Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, mindbomb E3 ubiquitin protein ligase 1/Mindbomb (Antibody to)
Alternative techniqueantibodies

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