Name : MICA+MICB Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6741027799
| Long name | MICA+MICB Primary Polyclonal Antibody |
| Also known as | MICA+MICB PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | MICA+MICB |
| Specificity | This is a highly specific antibody against MICA+MICB |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MICB |
| Gene ID number | 4277, 100507436 |
| Swiss Prot | Q29980, Q29983 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Binding to KLRK1 leads to cell lysis, Ligand for the KLRK1/NKG2D receptor, Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | HLA class I antigen MICB: MHC class I polypeptide-related sequence B, MHC class I mic-B antigen, MIC-A, MIC-B, MICA: MHC class I polypeptide-related sequence A |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | MICA+MICB |
| Short name | MICA+MICB Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Major histocompabitility complex class I polypeptide-related sequence A+Major histocompabitility complex class I polypeptide-related sequence B (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | Cell surfaces, MHC class I polypeptide-related sequence B, MICA and IDBG-77578 and ENSG00000204520 and 100507436, MICB and IDBG-77697 and ENSG00000204516 and 4277, PERB11, Plasma membranes, natural killer cell lectin-like receptor binding, protein binding, this GO :0002429 and immune response-activating cell surface receptor signaling pathway and biological process this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0009408 and response to heat and biological process this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0019835 and cytolysis and biological process this GO :0019882 and antigen processing and presentation and biological process this GO :0032526 and response to retinoic acid and biological process this GO :0046629 and gamma-delta T cell activation and biological process this GO :0046703 and natural killer cell lectin-like receptor binding and molecular function this GO :0050689 and negative regulation of defense response to virus by host and biological process this GO :0050776 and regulation of immune response and biological process, this GO :0005515 and protein binding and molecular function this GO :0006955 and immune response and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019882 and antigen processing and presentation and biological process this GO :0045087 and innate immune response and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0046703: natural killer cell lectin-like receptor binding, this GO :0046703: natural killer cell lectin-like receptor binding, 2, MHC class I polypeptide-related sequence A |
| Identity | 7090 |
| Gene | MICA |
| Long gene name | MHC class I polypeptide-related sequence A |
| Synonyms | PERB11, 1 |
| Locus | 6p21, 33 |
| Discovery year | 1994-05-16 |
| GenBank acession | L14848 |
| Entrez gene record | 100507436 |
| Pubmed identfication | 8022771 |
| RefSeq identity | NM_001177519 |
| Classification | C1-set domain containing |
| Havana BLAST/BLAT | OTTHUMG00000031073 |
| Locus Specific Databases | IMGT/HLA Database |