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Microcephalin 1/BRIT1 Antibody, ALEXA FLUOR 647

Microcephalin 1/BRIT1 Antibody, ALEXA FLUOR 647 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 647 Conjugated, Microcephalin 1/BRIT1 Antibody
Also known asAnti-Microcephalin 1/BRIT1 PAb ALEXA FLUOR 647
CategoryConjugated Primary Antibodies
Conjugated with 647, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMicrocephalin 1/BRIT1
SpecificityThis is a highly specific antibody against Microcephalin 1/BRIT1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Microcephalin 1/BRIT1
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Human Microcephalin contains three BRCA1 C-terminal (BRCT) domains and shares 57% identity with its mouse ortholog, It functions in DNA damage response and regulation of cell cycle checkpoints, Microcephalin displays significantly higher rates of protein evolution in primates than in rodents, Microcephalin has a very young, Predominant expression of human Microcephalin is observed in fetal brain, although the nature of the positive selection is poorly understood, liver and kidney tissues and is expressed during neurogenesis in mice, polymorphism haplotype associated with modern humans, single nucleotide, the most conserved regions being BRCT domains where there is 80% identity, this gene is presumably still evolving in Homo sapiens, this trend is most noticeable for the subset of genes associated with nervous system development, Microcephalin modulates brain size and has been proliferating under strong positive selection for several thousand years
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission650nm/665nm
Synonyms FLJ12847 BRIT1
Properties ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Microcephalin 1/BRIT1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 647, Alexa Fluor
Gene targetMicrocephalin 1/BRIT1
Short nameMicrocephalin 1/BRIT1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 647
Alternative name ALEXA FLUOR 647, Microcephalin 1/BRIT1 (Antibody to)
Alternative techniqueantibodies
Identity 6954
Gene MCPH1
Long gene name microcephalin 1
Synonyms gene name microcephaly, primary autosomal recessive 1
Synonyms name BRCT-repeat inhibitor of TERT expression 1
Locus 8p23, 1
Discovery year 1998-02-11
GenBank acession AK022909
Entrez gene record 79648
Pubmed identfication 9683597 17925396
RefSeq identity NM_024596
Havana BLAST/BLAT OTTHUMG00000163618

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