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Microcephalin 1/BRIT1 Antibody, Cy5 Conjugated

Microcephalin 1/BRIT1 Antibody, Cy5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5 Conjugated, Microcephalin 1/BRIT1 Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMicrocephalin 1/BRIT1
SpecificityThis is a highly specific antibody against Microcephalin 1/BRIT1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human Microcephalin 1/BRIT1
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Human Microcephalin contains three BRCA1 C-terminal (BRCT) domains and shares 57% identity with its mouse ortholog, It functions in DNA damage response and regulation of cell cycle checkpoints, Microcephalin displays significantly higher rates of protein evolution in primates than in rodents, Microcephalin has a very young, Predominant expression of human Microcephalin is observed in fetal brain, although the nature of the positive selection is poorly understood, liver and kidney tissues and is expressed during neurogenesis in mice, polymorphism haplotype associated with modern humans, single nucleotide, the most conserved regions being BRCT domains where there is 80% identity, this gene is presumably still evolving in Homo sapiens, this trend is most noticeable for the subset of genes associated with nervous system development, Microcephalin modulates brain size and has been proliferating under strong positive selection for several thousand years
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms FLJ12847 BRIT1
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetMicrocephalin 1/BRIT1 Conjugated
Short name Conjugated, Microcephalin 1/BRIT1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, Microcephalin 1/BRIT1 (Antibody to)
Alternative techniqueantibodies
Identity 6954
Gene MCPH1
Long gene name microcephalin 1
Synonyms gene name microcephaly, primary autosomal recessive 1
Synonyms name BRCT-repeat inhibitor of TERT expression 1
Locus 8p23, 1
Discovery year 1998-02-11
GenBank acession AK022909
Entrez gene record 79648
Pubmed identfication 9683597 17925396
RefSeq identity NM_024596
Havana BLAST/BLAT OTTHUMG00000163618

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