Filters

Midline 1 Antibody, ALEXA FLUOR 488

Midline 1 Antibody, ALEXA FLUOR 488 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 488 Conjugated, Midline 1 Polyclonal Antibody
Also known asAnti-Midline-1 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMidline-1
SpecificityThis is a highly specific antibody against Midline-1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Midline-1/RNF59
Gene ID Number4281
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Defects in MID1 are the cause of Opitz syndrome type I (OS-I), It also interacts with IGBP1 (Lymphocyte signaling protein A4), It is a cytoplasmic protein found as a homodimer or heterodimer with Midline-2, Midline-1 belongs to the TRIM/RBCC family and contains two B box-type zinc fingers, Midline-1 is believed to have E3 ubiquitin ligase activity which targets the catalytic subunit of protein phosphatase 2 for degradation, OS-I is an X-linked recessive disorder characterized by hypertelorism, OS-I mutations produce proteins with a decreased affinity for microtubules, Putative transcription factor XPRF, RING finger protein 59) is a 667 amino acid protein encoded by the human gene MID1, developmental delay and congenital heart defects, genital-urinary defects such as hypospadias in males and splayed labia in females, imperforate anus, lip-palate-laryngotracheal clefts, one B30, one COS domain, one fibronectin type-III domain and one RING-type zinc finger, 2/SPRY domain, Midline-1 (Tripartite motif-containing protein 18
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms OS FXY TRIM18 RNF59
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Midline 1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetMidline 1
Short nameMidline 1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, Midline 1 (Antibody to)
Alternative techniqueantibodies
Identity 7095
Gene MID1
Long gene name midline 1
Synonyms name Opitz/BBB syndrome
Locus Xp22
Discovery year 1997-12-12
GenBank acession Y13667
Pubmed identfication 9354791 9425238
Classification Tripartite motif containing Ring finger proteins Fibronectin type III domain containing
Havana BLAST/BLAT OTTHUMG00000021127
Locus Specific Databases Mental Retardation database

Subscribe to our Newsletter