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Mitofusin 2 Antibody

Mitofusin 2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMitofusin 2 Primary Polyclonal Antibody
Also known asMitofusin 2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMitofusin 2
SpecificityThis is a highly specific antibody against Mitofusin 2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range1-50/757
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Mitofusin 2
Gene ID number9927
Swiss ProtO95140
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions, Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy), Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress, Is required for PARK2 recruitment to dysfunctional mitochondria, It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes, MFN2 acts independently of the cytoskeleton, Overexpression induces the formation of mitochondrial networks, Plays an important role in the regulation of vascular smooth muscle cell proliferation, which is balanced between fusion and fission, which mediates mitochondrial fusion, Essential transmembrane GTPase
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CMT2A, CMT2A2, CPRP1, KIAA0214, MARF, MFN2, Mitofusin-2, Transmembrane GTPase MFN2, HSG
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMitofusin 2
Short nameMitofusin 2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMitofusin 2 (Antibody to)
Alternative techniqueantibodies
Identity 16877
Gene MFN2
Long gene name mitofusin 2
Synonyms CPRP1 KIAA0214 MARF CMT2A2
Locus 1p36, 22
Discovery year 2003-02-25
GenBank acession AF036536
Entrez gene record 9927
Pubmed identfication 12499352 11181170
RefSeq identity NM_014874
Havana BLAST/BLAT OTTHUMG00000002392
Locus Specific Databases Inherited Peripheral Neuropathies Mutation Database LRG_255

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