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Mitofusin 2 Antibody, ALEXA FLUOR 488

Mitofusin 2 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, Mitofusin 2 Polyclonal Antibody
Also known asAnti-Mitofusin 2 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMitofusin 2
SpecificityThis is a highly specific antibody against Mitofusin 2
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range1-50/757
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Mitofusin 2
Gene ID Number9927
Swiss ProtO95140
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions, Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy), Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress, Is required for PARK2 recruitment to dysfunctional mitochondria, It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes, MFN2 acts independently of the cytoskeleton, Overexpression induces the formation of mitochondrial networks, Plays an important role in the regulation of vascular smooth muscle cell proliferation, which is balanced between fusion and fission, which mediates mitochondrial fusion, Essential transmembrane GTPase
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms CPRP1 KIAA0214 MARF CMT2A2
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Mitofusin 2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetMitofusin 2
Short nameMitofusin 2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, Mitofusin 2 (Antibody to)
Alternative techniqueantibodies
Identity 16877
Gene MFN2
Long gene name mitofusin 2
Locus 1p36, 22
Discovery year 2003-02-25
GenBank acession AF036536
Entrez gene record 9927
Pubmed identfication 12499352 11181170
RefSeq identity NM_014874
Havana BLAST/BLAT OTTHUMG00000002392
Locus Specific Databases Inherited Peripheral Neuropathies Mutation Database LRG_255

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