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MKK3(Ser218)/MKK6(Ser207) Antibody, ALEXA FLUOR 647

MKK3(Ser218)/MKK6(Ser207) Antibody, ALEXA FLUOR 647 size: 100ul 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 350
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 647 Conjugated, MKK3(Ser218)/MKK6(Ser207) Antibody
Also known asAnti-MKK3 Ser218 + MKK6 Ser207 PAb ALEXA FLUOR 647
CategoryConjugated Primary Antibodies
Conjugated with 647, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMKK3 Ser218 + MKK6 Ser207
SpecificityThis is a highly specific antibody against MKK3 Ser218 + MKK6 Ser207
ModificationPhosphorylation
Modification SiteSer207
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range200-230/347
Subcellular location Membrane bound, Nucleus, Cytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human MKK3 around the phosphorylation site of Ser218
Gene ID Number5606, 5608
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, It phosphorylates and thus activates MAPK14/p38-MAPK, Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene, The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis, This kinase can be activated by insulin, This kinase is activated by mitogenic and environmental stress, and confers oncogenic transformation of primary cells, and is necessary for the expression of glucose transporter, and participates in the MAP kinase-mediated signaling cascade, which thus leads to the constitutive activation of MAPK14, The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission650nm/665nm
Synonyms MEK6 MKK6 SAPKK3 MAPKK6
Properties ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the MKK3(Ser218)/MKK6(Ser207) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 647, Alexa Fluor
Gene targetMKK3(Ser218)/MKK6(Ser207)
Short nameMKK3(Ser218)/MKK6(Ser207) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 647
Alternative name ALEXA FLUOR 647, MKK3(Ser218)/MKK6(Ser207) (Antibody to)
Alternative techniqueantibodies
Identity 6846
Gene MAP2K6
Long gene name mitogen-activated protein kinase kinase 6
Synonyms gene PRKMK6
Synonyms name kinase 6 (MAP kinase kinase 6) , mitogen-activated, protein kinase
Locus 17q24, 3
Discovery year 1997-11-11
GenBank acession U39064
Entrez gene record 5608
Pubmed identfication 8621675
RefSeq identity NM_002758
Classification Mitogen-activated protein kinase kinases
Havana BLAST/BLAT OTTHUMG00000180311

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