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MKK4 Antibody MEK4

MKK4 Antibody MEK4 size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenMKK4 MEK4
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
Notes Titration of the MKK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis MKK4 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P45985
PurityAntigen affinity
Description It has been shown to activate MAPK8/JNK1, It is mapped to 17p12, JNK2, JNKK1 and MKK4, MAP2K4 was a specific activator of JNK1, MAPK8, MAPK8IP3 and AKT1, MAPK9/JNK2, SEK1, This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family, This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli, This kinase is phosphorylated, also called MEK4, and MAPK14/p38, and it has been shown to interact with FLNC, and p38, and thus activated by MAP3K1/MEKK, but not MAPK1/ERK2 or MAPK3/ERK1, is an enzyme that in humans is encoded by the MAP2K4 gene, Dual specificity mitogen-activated protein kinase kinase 4 (MAP2K4)
ImmunogenAn amino acid sequence from the C-terminus of human MKK4/MEK4 (ELLKHPFILMYEERAVEVA) was used as the immunogen for this MKK4 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MKK4 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetMKK4 MEK4
Short nameMKK4 Antibody MEK4
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMKK4 (Antibody to) MEK4
Alternative techniqueantibodies
Identity 6844
Gene MAP2K4
Long gene name mitogen-activated protein kinase kinase 4
Synonyms gene SERK1
Synonyms MEK4 JNKK1 PRKMK4 MKK4
Locus 17p12
Discovery year 1997-11-11
GenBank acession L36870
Entrez gene record 6416
Pubmed identfication 7716521
Classification Mitogen-activated protein kinase kinases
Havana BLAST/BLAT OTTHUMG00000178267

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