Name : MLCK Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN7843575682
| Long name | MLCK Primary Polyclonal Antibody |
| Also known as | MLCK PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | MLCK |
| Specificity | This is a highly specific antibody against MLCK |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 700-750/1914 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MLCK |
| Gene ID number | 4638 |
| Swiss Prot | Q15746 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | A pseudogene is located on the p arm of chromosome 3, Additional variants have been identified but lack full length transcripts, Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin, In addition, Jul 2008], This gene encodes both smooth muscle and nonmuscle isoforms, This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity, [provided by RefSeq, a muscle member of the immunoglobulin gene superfamily, a small protein identical in sequence to the C-terminus of myosin light chain kinase, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme, it encodes telokin, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments, using a separate promoter in an intron in the 3' region, This gene |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | AAT7, Kinase-related protein, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, MYLK, MYLK1, Myosin light chain kinase, Telokin, smMLCK, smooth muscle, KRP |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | MLCK |
| Short name | MLCK Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | MLCK (Antibody to) |
| Alternative technique | antibodies |
| Identity | 29826 |
| Gene | MYLK3 |
| Long gene name | myosin light chain kinase 3 |
| Synonyms | caMLCK MLCK |
| Synonyms name | MLC kinase |
| Locus | 16q11, 2 |
| Discovery year | 2008-01-23 |
| GenBank acession | AJ247087 |
| Entrez gene record | 91807 |
| Pubmed identfication | 17885681 |
| RefSeq identity | NM_182493 |
| Havana BLAST/BLAT | OTTHUMG00000132543 |