Name : MLK3(Thr277 + Ser281) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN8766927645
| Long name | MLK3(Thr277 + Ser281) Antibody |
| Also known as | MLK3(Thr277 + Ser281) Antibody |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | MLK3 Thr277 + Ser281 |
| Specificity | This is a highly specific antibody against MLK3 Thr277 + Ser281 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Thr277 + Ser281 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 260-300/847 |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic phosphopeptide derived from human MLK3 around the phosphorylation site of Thr277/Ser281 |
| Gene ID number | 4296 |
| Swiss Prot | Q16584 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Influences microtubule organization during the cell cycle, MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7, Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), but does not phosphorylate BRAF directly, Activates the JUN N-terminal pathway |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | MAP3K11, MEKK11, MLK-3, Mitogen-activated protein kinase kinase kinase 11, Mixed lineage kinase 3, PTK1, SPRK, Src-homology 3 domain-containing proline-rich kinase, MLK3 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | MLK3(Thr277 + Ser281) |
| Short name | MLK3(Thr277 + Ser281) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | MLK3(Thr277 and Ser281) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6850 |
| Gene | MAP3K11 |
| Long gene name | mitogen-activated protein kinase kinase kinase 11 |
| Synonyms gene | MLK3 PTK1 |
| Synonyms | SPRK MEKK11 |
| Locus | 11q13, 1 |
| Discovery year | 1992-10-02 |
| Entrez gene record | 4296 |
| Pubmed identfication | 9267807 8183572 |
| Classification | Mitogen-activated protein kinase kinase kinases |
| Havana BLAST/BLAT | OTTHUMG00000166529 |