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MLL5 Antibody, Biotin Conjugated

MLL5 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, MLL5 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMLL5
SpecificityThis is a highly specific antibody against MLL5
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range310-360/1858
Subcellular location Cell membrane, Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human MLL5
Gene ID number55904
Swiss ProtQ8IZD2
Tested applicationsIHC-P
Recommended dilutionsIHC-P(1:100-500)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also acts as an important cell cycle regulator, H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, Isoform NKp44L: Cellular ligand for NCR2/NKp44, Key regulator of hematopoiesis involved in terminal myeloid differentiation and in the regulation of hematopoietic stem cell (HSCs) self-renewal by a mechanism that involves DNA methylation, Overexpression inhibits cell cycle progression, Plays an essential role in retinoic-acid-induced granulopoiesis by acting as a coactivator of RAR-alpha (RARA) in target gene promoters, Required to suppress inappropriate expression of S-phase-promoting genes and maintain expression of determination genes in quiescent cells, may play a role as a danger signal in cytotoxicity and NK-cell-mediated innate immunity, participating in cell cycle regulatory network machinery at multiple cell cycle stages, while knockdown induces cell cycle arrest at both the G1 and G2/M phases, Histone methyltransferase that specifically mono- and dimethylates 'Lys-4' of histone H3 (H3K4me1 and H3K4me2)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms HDCMC04P
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetMLL5 Conjugated
Short name Conjugated, MLL5 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name Drosophila) (Antibody to), biotinilated coupled, myeloid/lymphoid and mixed-lineage leukemia 5 (trithorax homolog
Alternative techniqueantibodies
Alternative to gene target DNA-templated and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016607 and nuclear speck and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0030218 and erythrocyte differentiation and biological process this GO :0030854 and positive regulation of granulocyte differentiation and biological process this GO :0042119 and neutrophil activation and biological process this GO :0042800 and histone methyltransferase activity (H3-K4 specific) and molecular function this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0048384 and retinoic acid receptor signaling pathway and biological process this GO :0051568 and histone H3-K4 methylation and biological process this GO :0070688 and MLL5-L complex and cellular component this GO :0071300 and cellular response to retinoic acid and biological process, Drosophila), MLL5 and IDBG-34737 and ENSG00000005483 and 55904, MLL5 and IDBG-631821 and ENSBTAG00000009207 and 539121, Mll5 and IDBG-139425 and ENSMUSG00000029004 and 69188, histone methyltransferase activity (H3-K4 specific), nuclei, this GO :0002446 and neutrophil mediated immunity and biological process this GO :0003713 and transcription coactivator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006306 and DNA methylation and biological process this GO :0006351 and transcription, this GO :0003713: transcription coactivator activity, this GO :0003713: transcription coactivator activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0019899: enzyme binding and also this GO :0042800: histone methyltransferase activity (H3-K4 specific), this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0019899: enzyme binding, this GO :0042800: histone methyltransferase activity (H3-K4 specific), myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog
Identity 18541
Gene KMT2E
Long gene name lysine methyltransferase 2E
Synonyms gene MLL5
Synonyms gene name Drosophila) lysine (K)-specific methyltransferase 2E , myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog
Locus 7q22, 3
Discovery year 2002-06-07
GenBank acession AF067804
Entrez gene record 55904
Pubmed identfication 9218106 7672722
Classification PHD finger proteins Lysine methyltransferases
Havana BLAST/BLAT OTTHUMG00000157403

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