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MLL5 Antibody, Cy5.5 Conjugated

MLL5 Antibody, Cy5.5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5, 5 Conjugated, MLL5 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation Cy5, 5, 5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMLL5
SpecificityThis is a highly specific antibody against MLL5
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range310-360/1858
Subcellular location Cell membrane, Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human MLL5
Gene ID number55904
Swiss ProtQ8IZD2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also acts as an important cell cycle regulator, H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, Isoform NKp44L: Cellular ligand for NCR2/NKp44, Key regulator of hematopoiesis involved in terminal myeloid differentiation and in the regulation of hematopoietic stem cell (HSCs) self-renewal by a mechanism that involves DNA methylation, Overexpression inhibits cell cycle progression, Plays an essential role in retinoic-acid-induced granulopoiesis by acting as a coactivator of RAR-alpha (RARA) in target gene promoters, Required to suppress inappropriate expression of S-phase-promoting genes and maintain expression of determination genes in quiescent cells, may play a role as a danger signal in cytotoxicity and NK-cell-mediated innate immunity, participating in cell cycle regulatory network machinery at multiple cell cycle stages, while knockdown induces cell cycle arrest at both the G1 and G2/M phases, Histone methyltransferase that specifically mono- and dimethylates 'Lys-4' of histone H3 (H3K4me1 and H3K4me2)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission675nm/694nm
Synonyms HDCMC04P
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene targetMLL5 Conjugated
Short name Conjugated, MLL5 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label5, Cy5
Alternative name Drosophila) (Antibody to), cyanine 5, 5 coupled, myeloid/lymphoid and mixed-lineage leukemia 5 (trithorax homolog
Alternative techniqueantibodies
Alternative to gene target DNA-templated and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016607 and nuclear speck and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0030218 and erythrocyte differentiation and biological process this GO :0030854 and positive regulation of granulocyte differentiation and biological process this GO :0042119 and neutrophil activation and biological process this GO :0042800 and histone methyltransferase activity (H3-K4 specific) and molecular function this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0048384 and retinoic acid receptor signaling pathway and biological process this GO :0051568 and histone H3-K4 methylation and biological process this GO :0070688 and MLL5-L complex and cellular component this GO :0071300 and cellular response to retinoic acid and biological process, Drosophila), MLL5 and IDBG-34737 and ENSG00000005483 and 55904, MLL5 and IDBG-631821 and ENSBTAG00000009207 and 539121, Mll5 and IDBG-139425 and ENSMUSG00000029004 and 69188, histone methyltransferase activity (H3-K4 specific), nuclei, this GO :0002446 and neutrophil mediated immunity and biological process this GO :0003713 and transcription coactivator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006306 and DNA methylation and biological process this GO :0006351 and transcription, this GO :0003713: transcription coactivator activity, this GO :0003713: transcription coactivator activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0019899: enzyme binding and also this GO :0042800: histone methyltransferase activity (H3-K4 specific), this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0019899: enzyme binding, this GO :0042800: histone methyltransferase activity (H3-K4 specific), myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog
Identity 18541
Gene KMT2E
Long gene name lysine methyltransferase 2E
Synonyms gene MLL5
Synonyms gene name Drosophila) lysine (K)-specific methyltransferase 2E , myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog
Locus 7q22, 3
Discovery year 2002-06-07
GenBank acession AF067804
Entrez gene record 55904
Pubmed identfication 9218106 7672722
Classification PHD finger proteins Lysine methyltransferases
Havana BLAST/BLAT OTTHUMG00000157403

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