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MLLT11 Antibody, ALEXA FLUOR 594

MLLT11 Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, MLLT11 Polyclonal Antibody
Also known asAnti-MLLT11 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMLLT11
SpecificityThis is a highly specific antibody against MLLT11
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MLLT11
Gene ID Number10962
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Also, Based on the expression patterns of MLLT11, Chromosomal translocations involving band 11q23 result in rogue activator proteins that are associated with approximately 10% of patients with acute lymphoblastic leukemia (ALL) and 5% of patients with acute myeloid leukemia (AML), Finally, MLLT11, MLLT11 has been shown to be differentially expressed in highly metastatic cells, MLLT11 is upregulated during neuronal differentiation and is thought to play a role in the development of the central nervous system, Most patients affected are less than 1 year of age, Such findings suggest a role of MLLT11 in tumorigenesis, also known as mixed-lineage leukemia translocated to 11 or AF1q, expressed in embryonic brain cortex, in comparison with non-metastatic parent cells, is a 90 amino acid MLL fusion partner, it is thought that MLLT11 plays a role in leukemogenesis and, specifically, the progression of acute monocytic leukemia (AML), The gene encoding the Mixed-Lineage Leukemia (MLL) proteins is located on chromosome 11q23
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms AF1Q
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetMLLT11
Short nameMLLT11 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name 11 (Antibody to), ALEXA FLUOR 594, Drosophila), translocated to, myeloid/lymphoid and mixed-lineage leukemia (trithorax homolog
Alternative techniqueantibodies
Alternative to gene target 11, AF1Q, DNA-templated and biological process this GO :0051901 and positive regulation of mitochondrial depolarization and biological process this GO :0090200 and positive regulation of release of cytochrome c from mitochondria and biological process this GO :0097191 and extrinsic apoptotic signaling pathway and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process, Drosophila), MLLT11 and IDBG-244926 and ENSG00000213190 and 10962, MLLT11 and IDBG-633245 and ENSBTAG00000015369 and 539519, Mllt11 and IDBG-171976 and ENSMUSG00000053192 and 56772, molecular_function, multiple, this GO :0003674 and molecular function and molecular function this GO :0005622 and intracellular and cellular component this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0045893 and positive regulation of transcription, this GO :0003674: molecular_function, this GO :0003674: molecular_function, translocated to, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog
Identity 16997
Gene MLLT11
Long gene name 11 , myeloid/lymphoid or mixed-lineage leukemia, translocated to
Synonyms gene name 11 , Drosophila), myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, translocated to
Synonyms name ALL1 fused gene from chromosome 1q
Locus 1q21, 3
Discovery year 2005-05-23
GenBank acession BC006471
Entrez gene record 10962
Pubmed identfication 7833468
RefSeq identity NM_006818
Havana BLAST/BLAT OTTHUMG00000035160

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