Name : MME/CD10 (307CT12.12.5) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :211
SKU : GEN9622105889
| Long name | 12, 5) Monoclonal Antibody, MME/CD10 (307CT12 |
| Also known as | 12, 5) Monoclonal Antibody, MME/CD10 (307CT12 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | MME/CD10 |
| Specificity | This is a highly specific antibody against MME/CD10 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 5, 12, 307CT12 |
| Source | This MME/CD10 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 272-300 amino acids from human MME/CD10 |
| Gene ID number | 4311 |
| Swiss Prot | P08473 |
| Tested Applications | WB |
| Recommended dilutions | WB(1:100~250) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Able to cleave angiotensin-1, Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991), Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed:20876573), Involved in the degradation of atrial natriuretic factor (ANF) (PubMed:2531377, PubMed:2972276), PubMed:8168535), angiotensin-2 and angiotensin 1-9 (PubMed:15283675), but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, Thermolysin-like specificity |
| Purification method | This antibody is prepared by Euglobin precipitation followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Atriopeptidase, CALLA, CD10, CMT2T, Common acute lymphocytic leukemia antigen, EPN, Enkephalinase, MME, Neprilysin, Neutral endopeptidase, Neutral endopeptidase 24, SFE, Skin fibroblast elastase, 11, NEP |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 12, 5) Monoclonal, MME/CD10 (307CT12 |
| Short name | 12, 5) Monoclonal Antibody, MME/CD10 (307CT12 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 12, 5) monoclonal (Antibody to), MME/CD10 (307CT12 |
| Alternative technique | antibodies |
| Identity | 7154 |
| Gene | MME |
| Long gene name | membrane metalloendopeptidase |
| Synonyms | CALLA CD10 NEP |
| Synonyms name | neutral endopeptidase enkephalinase neprilysin |
| Locus | 3q25, 2 |
| Discovery year | 1989-05-15 |
| Entrez gene record | 4311 |
| RefSeq identity | NM_000902 |
| Classification | CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000158455 |