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MMP-17 Antibody, Biotin Conjugated

MMP-17 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, MMP-17 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMMP-17
SpecificityThis is a highly specific antibody against MMP-17
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human MMP17
Gene ID number4326
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background All MMPs are synthesized as proenzymes, Alzheimer's, Collectively, In addition, In general, MMPs are considered to play an important role in wound healing, Shed forms of MMP17 have also been reported, Thus, Treatment of cells with Concanavolin A or the phorbol ester TPA stimulates production of MMP17 in some cell types, a hinge region, a propeptide, a signal peptide, and a C terminal hemopexin like domain allow categorization of MMPs into the collagenase, and a catalytic domain containing the highly conserved zinc binding site characterizes the structure of the MMPs, and in cancer cell invasion and metastasis, and in diseases such as multiple sclerosis, and is constituitively produced by some normal cell lines, and most of them are secreted from the cells as proenzymes, and the enzyme can be recovered in cell lysates, angiogenesis and tissue remodeling, apoptosis, arthritis, atherosclerosis, bone elongation, embryo development, fibronectin, fibronectin like repeats, gelatinase, glumerulonephritis, including fibrillar and non fibrillar collagens, laminin and basement membrane glycoproteins, lupus, malignant gliomas, periodontis, stomelysin and membrane type MMP subfamilies, the activation of these proenzymes is a critical step that leads to extracellular matrix breakdown, these enzymes can degrade all the components of the extracellular matrix, tissue ulceration, uterine involution, MMP17 has been reported to be elevated in several tumor cell lines, The matrix metalloproteinases (MMPs) are a family of at least eighteen secreted and membrane bound zincendopeptidases
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms MMP 17, MMP-17, MMP17, MT MMP 4, MT MMP4, MT4 MMP, MT4MMP, MTMMP 4, Matrix metalloproteinase 17, Matrix metalloproteinase 17 membrane inserted, Membrane type 4 matrix metalloproteinase, Membrane type matrix metalloproteinase 4, Matrix metalloproteinase-17
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetMMP-17 Conjugated
Short name Conjugated, MMP-17 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, MMP-17 (Antibody to)
Alternative techniqueantibodies

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