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MMP-2 Antibody, FITC Conjugated

MMP-2 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, MMP-2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMMP-2
SpecificityThis is a highly specific antibody against MMP-2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range409-434/662
Subcellular location Membrane bound, Mitochondrion, Nucleus, Secreted, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human MMP-2
Gene ID number4313
Swiss ProtP08253
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also cleaves KISS at a Gly-|-Leu bond, Appears to have a role in myocardial cell death pathways, As well as degrading extracellular matrix proteins, Cleaves GSK3beta in vitro, Contributes to myocardial oxidative stress by regulating the activity of GSK3beta, Involved in the formation of the fibrovascular tissues in association with MMP14, Isoform 2: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, Ligand for integrinv/beta3 on the surface of blood vessels, NFAT and IRF transcriptional pathways, PEX, and atherosclerotic plaque rupture, angiogenesis, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction, inflammation, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin, the C-terminal non-catalytic fragment of MMP2, tissue repair, tumor invasion, Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms 72 kDa gelatinase, 72 kDa type IV collagenase, CLG4A, Gelatinase A, MMP-2, MMP-II, MMP2, MONA, Matrix metalloproteinase-2, TBE-1, CLG4
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetMMP-2 Conjugated
Short name FITC Conjugated, MMP-2 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, MMP-2 (Antibody to)
Alternative techniqueantibodies

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