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MMP13 Antibody / Collagenase 3

MMP13 Antibody / Collagenase 3 size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenMMP13 / Collagenase 3
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
NotesOptimal dilution of the MMP13 antibody should be determined by the researcher
Added buffer025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2
Intented useThis MMP13 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P45452
PurityAntigen affinity
Description It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis, Mutations in this gene are associated with metaphyseal anadysplasia, Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, The encoded preproprotein is proteolytically processed to generate the mature protease, This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs), This gene is part of a cluster of MMP genes on chromosome 11, This protease cleaves type II collagen more efficiently than types I and III, and tissue remodeling, as well as in disease processes, reproduction, such as arthritis and metastasis, such as embryonic development, Collagenase 3 is an enzyme that in humans is encoded by the MMP13 gene
ImmunogenAmino acids 109-154 (RTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFT-human) were used as the immunogen for the MMP13 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MMP13 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
Localization extracellular matrix, Secreted
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetMMP13 / Collagenase 3
Short nameMMP13 Antibody / Collagenase 3
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMMP13 (Antibody to) / Collagenase 3
Alternative techniqueantibodies
Identity 7159
Gene MMP13
Long gene name matrix metallopeptidase 13
Synonyms gene name matrix metalloproteinase 13 (collagenase 3)
Synonyms CLG3
Synonyms name collagenase 3
Locus 11q22, 2
Discovery year 1994-11-20
GenBank acession X75308
Entrez gene record 4322
Pubmed identfication 8207000
RefSeq identity NM_002427
Classification Endogenous ligands Matrix metallopeptidases
Havana BLAST/BLAT OTTHUMG00000165850

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