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MMP2 Antibody

MMP2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMMP2 Primary Polyclonal Antibody
Also known asMMP2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMMP2
SpecificityThis is a highly specific antibody against MMP2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range20-70/476
Subcellular locationSecreted
SourceMAT conjugated synthetic peptide derived from human MMP2
Gene ID number4313
Swiss ProtP08253
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also cleaves KISS at a Gly-|-Leu bond, Appears to have a role in myocardial cell death pathways, As well as degrading extracellular matrix proteins, Cleaves GSK3beta in vitro, Contributes to myocardial oxidative stress by regulating the activity of GSK3beta, Involved in the formation of the fibrovascular tissues in association with MMP14, Isoform 2: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, Ligand for integrinv/beta3 on the surface of blood vessels, NFAT and IRF transcriptional pathways, PEX, and atherosclerotic plaque rupture, angiogenesis, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction, inflammation, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin, the C-terminal non-catalytic fragment of MMP2, tissue repair, tumor invasion, Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 72 kDa gelatinase, 72 kDa type IV collagenase, CLG4A, Gelatinase A, MMP-2, MMP-II, MMP2, MONA, Matrix metalloproteinase-2, TBE-1, CLG4
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMMP2
Short nameMMP2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMMP2 (Antibody to)
Alternative techniqueantibodies
Identity 7166
Gene MMP2
Long gene name matrix metallopeptidase 2
Synonyms gene CLG4 CLG4A
Synonyms gene name 72kDa gelatinase, 72kDa type IV collagenase) , matrix metalloproteinase 2 (gelatinase A
Synonyms TBE-1
Locus 16q12, 2
Discovery year 1989-05-25
Entrez gene record 4313
Classification Matrix metallopeptidases
Havana BLAST/BLAT OTTHUMG00000133202

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