Name : MMP3 Antibody
Supplier : NJS POLY
Price :199
SKU : GEN2997142122
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | MMP3 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, IF, WB, IHC |
| Recommended dilutions | IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes | Titration of the MMP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This MMP3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P08254 |
| Purity | Antigen affinity |
| Description | IV, IX, Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases, The enzyme is thought to be involved in wound repair, The gene is part of a cluster of MMP genes which localize to chromosome 11q22, This gene encodes an enzyme which degrades fibronectin, and X, and cartilage proteoglycans, and tissue remodeling, and tumor initiation, as well as in disease processes, collagens III, laminin, progression of atherosclerosis, reproduction, such as arthritis and metastasis, such as embryonic development, 3, Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes |
| Immunogen | A portion of amino acids 30-59 from the human protein was used as the immunogen for this MMP3 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the MMP3 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | MMP3 |
| Short name | MMP3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | progelatinase) (Antibody to), matrix metallopeptidase 3 (stromelysin 1 |
| Alternative technique | antibodies |
| Alternative to gene target | BT, CHDS6 and MMP-3 and SL-1 and STMY and STMY1 and STR1, Extracellular, MMP3 and IDBG-69254 and ENSG00000149968 and 4314, Mmp3 and IDBG-132579 and ENSMUSG00000043613 and 17392, progelatinase), this GO :0004175 and endopeptidase activity and molecular function this GO :0004222 and metalloendopeptidase activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006508 and proteolysis and biological process this GO :0008237 and metallopeptidase activity and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0010727 and negative regulation of hydrogen peroxide metabolic process and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030334 and regulation of cell migration and biological process this GO :0030574 and collagen catabolic process and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0071230 and cellular response to amino acid stimulus and biological process, this GO :0004175: endopeptidase activity, this GO :0004175: endopeptidase activity and also this GO :0004222: metalloendopeptidase activity and also this GO :0005509: calcium ion binding and also this GO :0008237: metallopeptidase activity and also this GO :0008270: zinc ion binding, this GO :0004222: metalloendopeptidase activity, this GO :0005509: calcium ion binding, this GO :0008237: metallopeptidase activity, this GO :0008270: zinc ion binding, zinc ion binding, 18504 and IDBG-629038 and ENSBTAG00000037768 and 100848277, matrix metallopeptidase 3 (stromelysin 1 |
| Identity | 7173 |
| Gene | MMP3 |
| Long gene name | matrix metallopeptidase 3 |
| Synonyms gene | STMY1 STMY |
| Synonyms gene name | matrix metalloproteinase 3 (stromelysin 1, progelatinase) stromelysin 1 |
| Locus | 11q22, 2 |
| Discovery year | 2001-06-22 |
| GenBank acession | X05232 |
| Entrez gene record | 4314 |
| RefSeq identity | NM_002422 |
| Classification | Matrix metallopeptidases |
| Havana BLAST/BLAT | OTTHUMG00000048254 |