Name : MMS19 Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN8416303689
| Long name | Cy3 Conjugated, MMS19 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | MMS19 |
| Specificity | This is a highly specific antibody against MMS19 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 930-975/1030 |
| Source | KLH conjugated synthetic peptide derived from human MMS 19 |
| Gene ID number | 64210 |
| Swiss Prot | Q96T76 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | As part of the mitotic spindle-associated MMXD complex, FANCJ and RTEL1, In the CIA complex, Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription, via its role in iron-sulfur insertion into some component of the TFIIH-machinery, Key component of the cytosolic iron-sulfur protein assembly (CIA) complex |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | MET18 hMMS19 |
| Properties | 1 of the MMS19 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | MMS19 Conjugated |
| Short name | Conjugated, MMS19 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, MMS19 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 13824 |
| Gene | MMS19 |
| Long gene name | MMS19 homolog, cytosolic iron-sulfur assembly component |
| Synonyms gene | MMS19L |
| Synonyms gene name | MMS19 nucleotide excision repair homolog (S, cerevisiae) |
| Synonyms name | MET18 homolog (S, cerevisiae) |
| Locus | 10q24, 1 |
| Discovery year | 2000-12-21 |
| GenBank acession | AF007151 |
| Entrez gene record | 64210 |
| Pubmed identfication | 11071939 22678362 22678361 |
| Classification | Nucleotide excision repair Cytosolic iron-sulfur assembly components |
| Havana BLAST/BLAT | OTTHUMG00000018857 |