Name : Monoamine Oxidase B Antibody
Supplier : NJS POLY
Price :389
SKU : GEN8891148062
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | Monoamine Oxidase B |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications | IHC-P, WB |
| Recommended dilutions | 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes | Titration of the Monoamine Oxidase B antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use | This Monoamine Oxidase B antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q8BW75 |
| Purity | Antigen affinity |
| Description | It is a member of the flavin monoamine oxidase family, Like MAOA, MAOB catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues, MAOB inhibition is, MAOB is involved in the breakdown of dopamine, This protein preferentially degrades benzylamine and phenylethylamine, a neurotransmitter implicated in reinforcing and motivating behaviors as well as movement, a source of reactive oxygen species, as well as with decreased production of hydrogen peroxide, associated with enhanced activity of dopamine, it also degrades dopamine, therefore, Monoamine oxidase B is a protein that in humans is encoded by the MAOB gene |
| Immunogen | An amino acid sequence from the N-terminus of mouse Monoamine Oxidase B (RTYTIRNKNVKYVDL) was used as the immunogen for this Monoamine Oxidase B antibody (100% rat homology) |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Monoamine Oxidase B antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | Monoamine Oxidase B |
| Short name | Monoamine Oxidase B Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Monoamine Oxidase B (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6834 |
| Gene | MAOB |
| Long gene name | monoamine oxidase B |
| Locus | Xp11, 3 |
| Discovery year | 1986-01-01 |
| Entrez gene record | 4129 |
| RefSeq identity | NM_000898 |
| Havana BLAST/BLAT | OTTHUMG00000021388 |
| Locus Specific Databases | Mental Retardation database ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database |