Filters

MOUSE Anti-ANTHRAX PROTECTIVE ANTIGEN Antibody

MOUSE Anti-ANTHRAX PROTECTIVE ANTIGEN Antibody size: 200ug 531

Supplier MBS MONO
Price 531
Size 200ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asANTHRAX
Other names Anthrax toxins translocating protein, N/A, PA-83, Protective antigen, pXO1-110, pXO1-110
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameANTHRAX
Gene name synonimsN/A
Other gene names N/A, PA, PA20, PA63, PA83, pag, pagA, pxo1_110
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
CloneC3
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Bacterial
Specificity and cross-reactivity <, Both EF and LF functions intracellularly but are too large to enter the cell through existing channels, Francisella tularensis<, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The 83kDa PA (PA83) binds to the cell surface where a 20 kDa N-terminal fragment (PA20) is cleaved off, The PA is responsible for transporting the EF and LF into cells, The antibody recognises both the 83kDa and 63kDa truncated form of PA, The receptor complex is internalized within endocytotic vessels that are subsequently acidified, The remaining 63 kDa portion (PA63) oligomerizes to form a heptamer pre-pore, The three proteins depend on each other for their toxic effect, This particular antibody might cross react with speacies outside of the listed ones, Yersinia pestis, _x000D__x000D_This item does not cross-react with the Lethal Factor of <, exposing binding sites for LF and EF, or <, produces a toxin composed of three proteins, the Edema Factor (EF) and the Lethal Factor (LF), the Protective Antigen (PA), transforming the PA heptamer into a pore that releases the active enzymes EF (an adenylate cyclase) and LF (a protease targeting MAPKKs) into the cytosol, which then associates with up to three molecules of EF and/or LF, /i>, /i>, /i>, ANTHRAX This item recognises the Protective Antigen of the anthrax toxin, Bacillus anthracis, Bacillus anthracis<, Toxoplasma gondii<, _x000D__x000D__x000D_, i>, i>, i>
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Western Blot (WB), ELISA (EIA)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetANTHRAX PROTECTIVE
Short nameMOUSE Anti-ANTHRAX PROTECTIVE ANTIGEN Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMOUSE antibody to-ANTHRAX PROTECTIVE protein (Antibody to)
Alternative techniqueantibodies

Similar products

Subscribe to our Newsletter