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MOUSE Anti-ATIC Antibody

MOUSE Anti-ATIC Antibody size: 100ug 310

Supplier MBS MONO
Price 310
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asATIC
Other names 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase, 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase, AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme, AICAR transformylase, AICARFT/IMPCHASE, Bifunctional purine biosynthesis protein PURH, bifunctional purine biosynthesis protein PURH, phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase, bifunctional purine biosynthesis protein PURH
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameATIC
Gene name synonimsN/A
Other gene names AICAR, AICARFT, ATIC, IMPCHASE, PURH, PURH, ATIC
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
CloneF38 P7 H9
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Synthetic Peptide
Specificity and cross-reactivity Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The anti-inflammatory and neuroprotective functions of ATIC, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_ATIC has been identified as an activator of AMP-activated protein kinase (AMPK), a known regulator of energy homeostasis, a ribonucleotide formyltransferase (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) and member of the purH family, also have implications for its use in the treatment of Alzheimer's disease, inhibitor of cell proliferation and inducer of apoptosis in cancerous cells of various origins, making ATIC a potential therapeutic agent for cancer, otherwise known as AICAR, which helps catalyze the final steps of the purine biosynthesis pathway, ATIC This item specifically recognises ATIC
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Western Blot (WB), Immunohistology - Paraffin (IHC)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetATIC
Short nameMOUSE Anti-ATIC Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMOUSE antibody to-ATIC (Antibody to)
Alternative techniqueantibodies
Identity 794
Gene ATIC
Long gene name 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Synonyms PURH AICARFT IMPCHASE
Synonyms name phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
Locus 2q35
Discovery year 1997-05-15
Entrez gene record 471
Pubmed identfication 8567683 9378707
RefSeq identity NM_004044
Havana BLAST/BLAT OTTHUMG00000133023

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