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MOUSE Anti-CHICKEN CD45 Antibody

MOUSE Anti-CHICKEN CD45 Antibody size: 100ug 393

Supplier MBS MONO
Price 393
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD45
Other namesN/A
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD45
Gene name synonimsN/A
Other gene namesN/A
ClonalityMonoclonal
Immunoglobulin isotypeIgG2a
CloneUM16-6
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Chicken
Specificity and cross-reactivity Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Studies have indicated that dephosphorylation by CD45 is required for the activation of the src-family kinases p56<, The overall domain structure between mammalian and chicken CD45 appears to be conserved, This particular antibody might cross react with speacies outside of the listed ones, Variation in the expression of a particular CD45 isoform is regulated during the haematopoietic development of the different cell lineages, _x000D__x000D_CD45 is essential for antigen-induced signal transduction through the antigen receptor and as with other PTPase family members, _x000D__x000D_Investigations into the properties of CD45 in chicken models are limited, a heavily-glycosylated transmembrane protein tyrosine phosphatase (PTPase) expressed by all nucleated cells of haematopoietic origin, acts in balance with protein tyrosine kinases, and p59<, but the sequence homology between the extracellular regions is very low, but there is evidence of the existence of an additional cysteine residue near the transmembrane region, causing the dephosphorylation of negative regulatory tyrosine sites, /sup>, /sup>, CD45 Clone UM16-6 recognizes chicken CD45 (leucocyte common antigen), fyn<, lck<, sup>, sup>
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0 mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Flow Cytometry (FACS), Immunohistology - Frozen (IHC), Immunoprecipitation (IP)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD45
Short nameMOUSE Anti-CHICKEN CD45 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMOUSE antibody to-CHICKEN CD45 (Antibody to)
Alternative techniqueantibodies
Identity 9666
Gene PTPRC
Long gene name protein tyrosine phosphatase, receptor type C
Synonyms gene CD45
Synonyms LCA T200 GP180
Locus 1q31, 1 , 3-q32
Discovery year 1986-01-01
GenBank acession Y00062
Entrez gene record 5788
Pubmed identfication 2169617
RefSeq identity NM_002838
Classification Fibronectin type III domain containing CD molecules Protein tyrosine phosphatases, receptor type
Havana BLAST/BLAT OTTHUMG00000035702
Locus Specific Databases PTPRCbase: Mutation registry for CD45 deficiency LRG_95

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