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MOUSE Anti-DOG CD107b Antibody

MOUSE Anti-DOG CD107b Antibody size: 0.25 miligrams 564

Supplier MBS MONO
Price 564
Size 0.25 miligrams
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD107b
Other namesN/A
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD107b
Gene name synonimsN/A
Other gene namesN/A
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
CloneAC17
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Dog
Specificity and cross-reactivity CD107b has been shown to share high N-terminal amino acid sequence homology with human, Clone AC17 immunoprecipitates a protein of 95kDa in MDCK cells which, Immunofluorescence staining of MDCK cells with Mouse anti Canine CD107b demonstrates staining patterns consistent with localization to lysozomes, Lysosomes are membrane-bound organelles found within the cytoplasm of most cells, Members of the lysosomal-associated membrane protein family (LAMPS) are believed to play an important role in protecting the lysosomal membrane from protease degradation and are involved in lectin-mediated cell adhesion, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The molecular weight of canine CD107b is typical of many lysozome-associated membrane proteins, This is supported by coincident staining of an exogenous lysozomal glycoprotein, This particular antibody might cross react with speacies outside of the listed ones, While most (97%) CD107b resides in the lysozomal environment in adherent MDCK cells <, avian LEP100 transfected into MDCK cells and detected using the anti LEP100 antibody clone CV24, following Endo F digestion to remove N-linked oligosaccharides yields a core protein product of 40kDa, indicating the heavily glycosylated nature of CD107b, is a monoclonal antibody specific for canine CD107b, is found associated with the cell membrane, mouse and rat CD107b, otherwise known as lysosome-associated membrane protein 2 or LAMP-2, the early studies by indicate that a small percentage of total cellular CD107b as revealed by radioimmune assay with clone AC17, they contain hydrolytic enzymes and act as the major compartment for heterophagic and autophagic digestion, /em>, /strong>, CD107b <, Mouse anti Dog CD107b (AC17)<, em>, in vitro<, strong>
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetCD107b
Short nameMOUSE Anti-DOG CD107b Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMOUSE antibody to-canine CD107b (Antibody to)
Alternative techniqueantibodies
Identity 6501
Gene LAMP2
Long gene name lysosomal associated membrane protein 2
Synonyms gene name lysosomal-associated membrane protein 2
Synonyms CD107b
Locus Xq24
Discovery year 1990-08-03
GenBank acession X77196
Entrez gene record 3920
Classification CD molecules
Havana BLAST/BLAT OTTHUMG00000022301
Locus Specific Databases Mental Retardation database LRG_749

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