Name : MOUSE Anti-HUMAN ALPHA B CRYSTALLIN Antibody
Supplier : MBS MONO
Price :542
SKU : GEN8751342181
| Also known as | ALPHA B CRYSTALLIN |
| Other names | Alpha(B)-crystallin, Alpha-crystallin B chain, Heat shock protein beta-5, HspB5, Renal carcinoma antigen NY-REN-27, Rosenthal fiber component, alpha B, alpha-crystallin B chain, crystallin, heat shock protein beta-5, heat-shock 20 kD like-protein, renal carcinoma antigen NY-REN-27, rosenthal fiber component, alpha-crystallin B chain |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | CMD1II, CRYA2, CRYA2, CRYAB, CTPP2, HSPB5, HspB5, CRYAB |
| Gene name synonims | CMD1II, CRYA2, CRYA2, CRYAB, CTPP2, HSPB5, HspB5, CRYAB |
| Other gene names | CMD1II, CRYA2, CRYA2, CRYAB, CTPP2, HSPB5, HspB5, CRYAB |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG2b |
| Clone | 200000000 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Besides the involvement of both alpha A and alpha B crystallin in the prevention of protein precipitation and cataract formation in the eye, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Studies have shown that a mutation in alpha B crystallin is responsible for desmin-related myopathy (DRM) and cataract Alpha B crystallin is also a major component of the astrocytic inclusions known as Rosenthal fibers (RFs), This particular antibody might cross react with speacies outside of the listed ones, a 20kDa water-soluble major structural protein and member of the heat shock protein family, alpha crystallins have also been demonstrated in other tissues including the heart, brain, designated HSPB5, found in Alexander's disease, kidney, spleen and thymus, which acts as a molecular chaperone and is believed to play a role in the maintenance of ocular lens transparency/refractive index, ALPHA B CRYSTALLIN This item recognises alpha B crystallin |
| Purification method | N/A |
| Form/Appearance | Purified (Purified IgG - liquid) |
| Concentration | 0mg/ml, IgG concentration 1 |
| Storage and shipping | If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications: | Western Blot (WB), ELISA (EIA) |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target | ALPHA B CRYSTALLIN |
| Short name | MOUSE Anti-HUMAN ALPHA B CRYSTALLIN Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | sapiens a B CRYSTALLIN (Antibody to), MOUSE antibody to-H |
| Alternative technique | antibodies |
| Identity | 2389 |
| Gene | CRYAB |
| Long gene name | crystallin alpha B |
| Synonyms gene | CRYA2 |
| Synonyms gene name | alpha B , crystallin |
| Synonyms | HSPB5 |
| Locus | 11q23, 1 |
| Discovery year | 1987-09-11 |
| Entrez gene record | 1410 |
| Pubmed identfication | 8431633 |
| Classification | Small heat shock proteins |
| Havana BLAST/BLAT | OTTHUMG00000166885 |
| Locus Specific Databases | LOVD - Leiden Open Variation Database LRG_407 |