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MOUSE Anti-HUMAN B7-H4 Antibody

MOUSE Anti-HUMAN B7-H4 Antibody size: 200ug 553

Supplier MBS MONO
Price 553
Size 200ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asB7-H4
Other names B7 family member, B7 superfamily member 1, B7h, H4, Immune costimulatory protein B7-H4, Protein B7S1, T cell costimulatory molecule B7x, T-cell costimulatory molecule B7x, T-cell costimulatory molecule B7x, V-set domain containing T cell activation inhibitor 1, V-set domain-containing T-cell activation inhibitor 1, V-set domain-containing T-cell activation inhibitor 1, immune costimulatory protein B7-H4, 5, V-set domain-containing T-cell activation inhibitor 1 isoform 2
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameB7-H4
Gene name synonimsN/A
Other gene names B7-H4, B7H4, B7H4, B7S1, B7X, B7h, PRO1291, RP11-229A19, VCTN1, VTCN1, 4, 5, VTCN1
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
CloneMIH43
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity Aberrant expression has been associated with cancers of the lung, Although B7-H4 binds an unknown receptor, B-cells, B7-H4 could be a useful prognostic marker in Renal Cell Carcinoma (RCC), B7-H4 deficient mice are only minimally affected, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_B7-H4 is expressed on activated T-cells, a costimulatory protein which is reported to function as a negative regulator of T-cell mediated immunity, also known as B7x, breast and ovary in humans, cell cycle progression and interleukin-2 production, it is thought to deliver an inhibitory signal to T-cells preventing their proliferation, monocytes and dendritic cells, suggesting B7-H4 is important in the fine tuning of the T-cell mediated immune response, B7-H4 This item recognises human B7-H4
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0 mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: Flow Cytometry (FACS), Immunohistology - Paraffin (IHC), Immunohistology - Frozen (IHC)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetB7-H4
Short nameMOUSE Anti-HUMAN B7-H4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens B7-H4 (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 28873
Gene VTCN1
Long gene name V-set domain containing T-cell activation inhibitor 1
Synonyms gene name V-set domain containing T cell activation inhibitor 1
Synonyms B7-H4 FLJ22418 B7S1 B7X B7H4
Synonyms name B7 family member, H4 B7 superfamily member 1
Locus 1p13, 1-p12
Discovery year 2005-02-25
GenBank acession BX648021
Entrez gene record 79679
Pubmed identfication 12818165 12818166
RefSeq identity NM_024626
Classification V-set domain containing Immunoglobulin like domain containing
Havana BLAST/BLAT OTTHUMG00000012118

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