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MOUSE Anti-HUMAN C3b Antibody

MOUSE Anti-HUMAN C3b Antibody size: 50ug 906

Supplier MBS MONO
Price 906
Size 50ug
Also known asC3b
Other names ASP, Alternative name(s):, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1Cleaved into the following 11 chains:Complement C3 beta chainComplement C3 alpha chainC3a anaphylatoxinAcylation stimulating protein, C3a anaphylatoxin, C3adesArg, Complement C3, acylation-stimulating protein cleavage product, complement C3, complement component 3, complement component C3, complement component C3a, complement component C3b, prepro-C3, complement C3
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameC3b
Gene name synonimsN/A
Other gene names AHUS5, ARMD9, ASP, ASP, C3, C3a, C3b, CPAMD1, CPAMD1, C3
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
CloneH11
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity C3 is cleaved by C3-convertase creating C3a and C3b, It does not react with the anaphylatoxin C3a_x000D_or the fragment C3d and does not inhibit the haemolytic function of C3, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The antibody is directed to a determinant present on the betachain of the C3 molecule (Western blot), This particular antibody might cross react with speacies outside of the listed ones, part of the complement system, which binds to the surface of pathogens leading to their destruction by phagocytic cells, C3b This item is specific for C3b, _x000D_, _x000D_This antibody recognizes a determinant present on native (circulating) C3 and on the fragments C3b and C3c
Purification methodN/A
Form/AppearancePurified (Purified IgG - lyophilised)
ConcentrationIgG concentration 50 ug/ml after reconstitution
Storage and shipping After reconstitution Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term, If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 12 months from date of reconstitution, Temperature variations in the range between +1C to +7C are tolerable, the antibody should be stored undiluted, Prior to reconstitution Keep the antibody refrigerated at +4 degrees Celsius, Storage in frost-free freezers is not recommended
Tested applications: Western Blot (WB), Immunohistology - Frozen (IHC)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetC3b
Short nameMOUSE Anti-HUMAN C3b Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens C3b (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 1318
Gene C3
Long gene name complement C3
Synonyms gene name complement component 3
Synonyms CPAMD1 ARMD9 C3a C3b
Synonyms name C3a anaphylatoxin complement component C3a complement component C3b prepro-C3
Locus 19p13, 3
Discovery year 2001-06-22
GenBank acession J04763
Entrez gene record 718
RefSeq identity NM_000064
Classification Endogenous ligands Complement system C3 and PZP like, alpha-2-macroglobulin domain containing
Havana BLAST/BLAT OTTHUMG00000150335
Locus Specific Databases C3base: Mutation registry for C3 deficiency LRG_27

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