Name : MOUSE Anti-HUMAN C3d Antibody
Supplier : MBS MONO
Price :597
SKU : GEN4483333941
| Also known as | C3d |
| Other names | ASP, Alternative name(s):, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1Cleaved into the following 11 chains:Complement C3 beta chainComplement C3 alpha chainC3a anaphylatoxinAcylation stimulating protein, C3a anaphylatoxin, C3adesArg, Complement C3, acylation-stimulating protein cleavage product, complement C3, complement component 3, complement component C3, complement component C3a, complement component C3b, prepro-C3, complement C3 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | C3d |
| Gene name synonims | N/A |
| Other gene names | AHUS5, ARMD9, ASP, ASP, C3, C3a, C3b, CPAMD1, CPAMD1, C3 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1 |
| Clone | 053A-1149, 1, 3, 4 (also known as 1003) |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | , C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The C3d/antigen complex mediates B cell activation by simultaneously binding antigen-specific surface bound immunoglobulin and CD21, This particular antibody might cross react with speacies outside of the listed ones, _x000D_C3d is involved in the regulation of many aspects of the immune response, a 33kDa polypeptide fragment generated over the course of complement activation where complement 3 (C3) convertases cleave C3 to C3b, including antigen processing and presentation, lowering the complement activation threshold, which is further degraded into iC3b and C3dg/C3d, C3d This item is specific for human complement component 3d (C3d) |
| Purification method | N/A |
| Form/Appearance | Purified (Purified Ig - liquid) |
| Concentration | 0mg/ml, 1 |
| Storage and shipping | If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications: | ELISA (EIA), Flow Cytometry (FACS), Immunohistology - Frozen (IHC), Western Blot (WB) |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target | C3d |
| Short name | MOUSE Anti-HUMAN C3d Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | sapiens C3d (Antibody to), MOUSE antibody to-H |
| Alternative technique | antibodies |
| Identity | 2336 |
| Gene | CR2 |
| Long gene name | complement C3d receptor 2 |
| Synonyms gene name | complement component (3d/Epstein Barr virus) receptor 2 complement component 3d receptor 2 |
| Synonyms | CD21 C3DR |
| Synonyms name | Epstein-Barr virus receptor |
| Locus | 1q32, 2 |
| Discovery year | 2001-06-22 |
| GenBank acession | M26004 |
| Entrez gene record | 1380 |
| RefSeq identity | NM_001877 |
| Classification | Sushi domain containing Complement system CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000036307 |
| Locus Specific Databases | LRG_348 |