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MOUSE Anti-HUMAN C4BP Antibody

MOUSE Anti-HUMAN C4BP Antibody size: 100ug 619

Supplier MBS MONO
Price 619
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asC4BP
Other names C4b-binding protein alpha chain, C4b-binding protein alpha chain, Proline-rich protein, alpha, complement component 4 binding protein, proline-rich protein, C4b-binding protein alpha chain
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameC4BP
Gene name synonimsN/A
Other gene names C4BP, C4BP, C4BPA, C4bp, PRP, PRP, C4BPA
ClonalityMonoclonal
Immunoglobulin isotypeIgG2b
Clone42284
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity C4bp also regulates the C4bC2a complex (C3 convertase), C4bp is expressed in the blood serum, It is a cofactor to the C3b/C4b inactivator, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The other complexes formed are a 530 kDa homoheptamer of alpha chains or a 500 kDa complex of 6 alpha chains and 1 beta chain, The predominant form is a 570 kDa complex of 7 alpha chains and 1 beta chain, There are three variants of C4bp, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Both the C4bp alpha and beta chains interact with anticoagulant protein S and C4bp alpha binds protein S, _x000D__x000D_C4bp regulates the activation of the classical complement pathway, accelerating its degradation by dissociating the complement fragment C2a, composed of alpha and beta chains, crucial to the proteolytic cleavage of C4b and important in cleavage of C3b, C4BP This item recognises complement component 4 binding protein (C4bp)
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0 mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from the date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications:ELISA (EIA)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetC4BP
Short nameMOUSE Anti-HUMAN C4BP Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens C4BP (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Identity 1328
Gene C4BPB
Long gene name complement component 4 binding protein beta
Synonyms gene C4BP
Synonyms gene name beta , complement component 4-binding protein
Synonyms name beta chain , beta chain C4b binding protein, complement component 4 binding protein
Locus 1q32, 1
Discovery year 1990-06-13
GenBank acession L11245
Entrez gene record 725
Pubmed identfication 2300577 8325877
RefSeq identity NM_000716
Classification Sushi domain containing
Havana BLAST/BLAT OTTHUMG00000036035

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