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MOUSE Anti-HUMAN C5 Antibody

MOUSE Anti-HUMAN C5 Antibody size: 100ug 597

Supplier MBS MONO
Price 597
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asC5
Other names C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, C5a anaphylatoxin, Complement C5, anaphylatoxin C5a analog, complement C5, complement component 5, prepro-C5, complement C5 preproprotein
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameC5
Gene name synonimsN/A
Other gene names C5, C5a, C5b, CPAMD4, CPAMD4, C5
ClonalityMonoclonal
Immunoglobulin isotypeIgG1
Clone046-10, 2, 2 (10-04)
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity C5 is thought to be associated with inflammation, C5a is an anaphylotoxin which mediates local inflammation, C5b, In addition to its role in complement, It also stimulates chemotaxis of neutrophils, It induces the contraction of smooth muscle, It is composed of an 115kDa disulphide linked alpha-chain and a 75 kDa beta-chain, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The remaining fragment, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_C5 is activated via either the classical or the alternative complement pathway, _x000D__x000D_In haemolysis inhibition studies it was found that This item will block C5 haemolytic activity, _x000D__x000D_Removal of sodium azide is recommended prior to use in functional assays, a 190kDa serine protease present in blood serum, basophils and monocytes towards the site of inflammation, by C5 convertase, by proteolytic cleavage of C5a from the N-terminal of the alpha-chain, eosinophils, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes, initiates the assembly of the membrane attack complex, interferon gamma mediated suppression of IL10 and IL12 production, stimulating tumour necrosis factor alpha, C5 This item recognises secreted complement component 5 (C5)
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0 mg/ml, IgG concentration 1
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: ELISA (EIA), Functional Assay (FA), Western Blot (WB)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetC5
Short nameMOUSE Anti-HUMAN C5 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens complement component 5 (Antibody to), MOUSE antibody to-H
Alternative techniqueantibodies
Alternative to gene target BT, C5 and IDBG-83167 and ENSG00000106804 and 727, C5a anaphylatoxin chemotactic receptor binding, C5a and C5b and C5D and CPAMD4 and ECLZB, Extracellular, Hc and IDBG-163835 and ENSMUSG00000026874 and 15139, alternative pathway and biological process this GO :0006958 and complement activation, classical pathway and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0008009 and chemokine activity and molecular function this GO :0010575 and positive regulation vascular endothelial growth factor production and biological process this GO :0010700 and negative regulation of norepinephrine secretion and biological process this GO :0010760 and negative regulation of macrophage chemotaxis and biological process this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0019835 and cytolysis and biological process this GO :0030449 and regulation of complement activation and biological process this GO :0031714 and C5a anaphylatoxin chemotactic receptor binding and molecular function this GO :0033602 and negative regulation of dopamine secretion and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0045087 and innate immune response and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0050921 and positive regulation of chemotaxis and biological process this GO :0060326 and cell chemotaxis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0090197 and positive regulation of chemokine secretion and biological process, this GO :0000187 and activation of MAPK activity and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0002523 and leukocyte migration involved in inflammatory response and biological process this GO :0004866 and endopeptidase inhibitor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005579 and membrane attack complex and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006935 and chemotaxis and biological process this GO :0006950 and response to stress and biological process this GO :0006954 and inflammatory response and biological process this GO :0006956 and complement activation and biological process this GO :0006957 and complement activation, this GO :0004866: endopeptidase inhibitor activity, this GO :0004866: endopeptidase inhibitor activity and also this GO :0005102: receptor binding and also this GO :0005515: protein binding and also this GO :0008009: chemokine activity and also this GO :0031714: C5a anaphylatoxin chemotactic receptor binding, this GO :0005102: receptor binding, this GO :0005515: protein binding, this GO :0008009: chemokine activity, this GO :0031714: C5a anaphylatoxin chemotactic receptor binding, 24055 and IDBG-638834 and ENSBTAG00000012210 and 512045, complement component 5
Identity 5127
Gene HOXC5
Long gene name homeobox C5
Synonyms gene HOX3D HOX3
Synonyms gene name homeo box C5
Locus 12q13, 13
Discovery year 1990-06-15
Entrez gene record 3222
Pubmed identfication 1973146 1358459
Classification HOXL subclass homeoboxes
Havana BLAST/BLAT OTTHUMG00000160028

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